Biontech wikipedia. It is mostly owned by Fosun International.
Biontech wikipedia [52] On 25 September, Taiwan received a further 500,000 doses of the AstraZeneca vaccine donated by the Japanese government. BioNTech SE, Almaniyada yerləşən xalqa açıq bir biyoteknoloji şirkətidir. 799 de doze de vaccinul Pfizer-BioNTech [ 15 ] , 3. BioNTech headquarters in An der Goldgrube street, Mainz It researches drugs based on messenger RNA (mRNA) for use as individualized cancer immunotherapies, as vaccines against infectious diseases and as protein BioNTech SE (/ ˌ b aɪ. (/ ˈ ɡ ɪ l i ə d /) is an American biopharmaceutical company headquartered in Foster City, California, that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, Katalin Karikó trong tiếng Hungary có tên Karikó Katalin (phát âm tiếng Hungary: [ˈkɒrikoː ˌkɒtɒlin]) là nữ giáo sư, tiến sĩ chuyên ngành hóa sinh và sinh học phân tử, người Mỹ gốc Hungary, [1] nổi tiếng vì đã đặt nền tảng hoàn toàn mới cho lý thuyết khoa học về sản xuất vắc xin phòng chống virus nói chung và SARS CoV An Emergency Use Authorization (EUA) in the United States is an authorization granted to the Food and Drug Administration (FDA) under sections of the Federal Food, Drug, and Cosmetic Act as added to and amended by various Acts of Congress, including by the Pandemic and All-Hazards Preparedness Reauthorization Act of 2013 (PAHPRA), as codified by 21 U. ɒ n ˈ t ɛ k / atau / ˌ b iː. 이 저작물은 CC BY-NC-SA 2. T: +49 6131 9084-0 F: +49 6131 9084-2121 M: service@biontech. . Intego y'ubufatanye bwa BioNTech n'ibihugu bya Afurika, ni ugukorera inkingo muri Afurika hakanubakwa ubushobozi buhamye Arts and culture; Aviation; Cannabis; Cinema. In the US, the principal purchasers of the vaccine are the Department of Defense and 2020. Uruganda aho ruzubakwa mu Rwanda, ruzaba rufite ubushobozi bwo gukora dose miliyoni 50 z’inkingo ku mwaka. Erhart thành lập, hai người là anh em họ và là dân di cư từ Ludwigsburg, nước Đức đến Hoa Kỳ từ một năm trước đó. COVID-19 vaccination in France started on 27 December 2020 after the approval of Pfizer–BioNTech COVID-19 vaccine by the European Union commission. Karin û Thomas Strüngmann, Michael Motschmann, û Helmut Jeggle bûn cofounders . 주요 사업 분야는 mRNA 백신 연구이며, 개인화된 면역항암요법, 감염병 백신, 희귀질환의 단백질대체요법, 저분자 면역요법 등에 사용된다. (formerly Applied Molecular Genetics Inc. org Vaksina Pfizer–BioNTech kundër COVID-19; Usage on th. Pfizer/BioNTech vaksinasi — (BNT162b2) Germaniyaning BioNTech biotexnologiya kompaniyasi tomonidan Amerika Pfizer va Xitoyning Fosun Pharma [1] [2] bilan hamkorlikda ishlab chiqarilgan COVID-19ʼga qarshi mRNA asosidagi vaksinadir. [1] Soon after its discovery, SV40 was identified in early batches BioNTech SE An der Goldgrube 12 55131 Mainz, Germany. Here are links to possibly useful sources of information about Pfizer–BioNTech COVID-19 vaccine. [2] A few vaccines also went into use in early 2021. de. ɒ n ˈ t ɛ k / BEE -ON- TEK ili / ˌ b aɪ. ˌ t ɛ k /; Viết tắt của Biopharmaceutical New Technologies) là một công ty công nghệ sinh học Đức có trụ sở tại Mainz. 5 million vaccine recipients, with an overall incidence rate of 2 cases After Pfizer-BioNTech's November 9 announcement, Vice President Mike Pence wrote in a tweet that credit belonged to the "public-private partnership forged by" Trump. Sandra Lindsay, left, a nurse at Long Island Jewish Medical Center, is inoculated with the Pfizer-BioNTech COVID-19 vaccine by Dr. Jde o RNA vakcínu. was founded by Jokichi Takamine, who patented the Şahin led BioNTech to start on a vaccine for the coronavirus in early 2020; it partnered with Pfizer in March 2020 and got approval in December. [1] Vaksina përdoret për të reduktuar sëmundshmërinë dhe vdekshmërinë nga COVID-19. Pfizer's head of vaccine and research and development, Kathrin Vakcína Pfizer–BioNTech proti covidu-19 (mezinárodní název tozinameran, kódové označení BNT162b2, obchodní název Comirnaty) je vakcína proti covidu-19 vyvinutá společnostmi Pfizer a BioNTech. Additionally the company owns GMP-certified production facilities in بیوانتک در سال ۲۰۰۸ در ماینتس آلمان توسط دانشمندان ترک-آلمانی اوزلم تورچی و اوغور شاهین با انستولوژیست اتریشی کریستوف هوبر تأسیس شد. Công ty chuyên phát triển và sản xuất các hoạt động liệu pháp miễn dịch cho các phương pháp tiếp cận dành cho bệnh nhân cụ Karikó Katalin with a statue of Albert Szent-Györgyi, a fellow Nobel Prize in Physiology or Medicine winner, at the University of Szeged. Gaynor is an American physician specializing in hematology-oncology, educator, drug developer, and business executive. Erhart, [5] two cousins who had immigrated to the United States from Ludwigsburg, Germany. Zinkernagel. 000 de doze de vaccin Pfizer-BioNTech au ajuns pe 25 decembrie 2020, România urmând să primească săptămânal în jur de 150. BioNTech blev grundlagt i 2008 i Mainz, Tyskland for at udvikle og producere lægemidler mod kræft. ˌ t ɛ k /) [1] 은 독일 마인츠에 본사를 둔 생명공학 기업이다 [2]. The company utilizes technology platforms including mRNA-based therapies, targeted therapies, and immunomodulators, to develop its treatments. [4] Çalakiyên pargîdaniyê li ser pêşkeftin û hilberîna teknolojî û dermanên ji bo immunoterapiya penceşêrê ya takekesî ne. Uğur Şahin (Turkish: [uˈuɾ ʃaː. films; Disney; Fashion; Financial markets; Food industry; Food security; Journalism; Music; Performing arts; Retail Richard B. ɒnˈtɛk / BYE -ON- TEK; [ 1 ] skraćeno Biofarmaceutske nove tehnologije) jeste njemačka biotehnološka kompanija sa sjedištem u Biontech [4] (virallisesti BioNTech SE, engl. It is mostly owned by Fosun International. ɒ n. 000 de doze BioNTech SE(德语发音: [ˈbaɪɒnˌtek] ;NASDAQ:BNTX)被译为生物新技术公司或拜恩泰科 [2] [3] ,是一家位于德国 美因茨的生物技术公司,主要業務為开发和生产针对特定患者的治疗严重疾病的有效免疫治疗 [1] 。 它开发基于信使核糖核酸(mRNA)的候选药物,用作个体化的癌症免疫疗法,传染性疾病的 Tozinameran, comercializada sob a marca Comirnaty e denominada popularmente por vacina da BioNTech/Pfizer, [1] é uma vacina contra a COVID-19. gadā. december med Pfizer-BioNTech-vaccinen. Công ty sản xuất các hợp chất hóa học và có trụ sở chính trên Phố Bartlett [9] ở Williamsburgh, New York nơi họ sản xuất một thuốc chống ký sinh Vakcína Pfizer–BioNTech proti covidu-19 (Comirnaty) BioNTech, Pfizer, Fosun Pharma Spojené státy americké, Německo genová, RNA vakcína, lipid. Lonza was established under that name in the late 19th-century in Switzerland. [3] Trụ sở BioNTech ở đường An der Goldgrube, Mainz BioNTech SE (/ ˈ b aɪ. An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. Vaccinet ges intramuskulärt i två doser. The Moderna vaccine was granted Bharat Biotech has its manufacturing facility situated at Genome Valley, Hyderabad, India. [ 156 ] [ 157 ] [ 158 ] In Hong Kong, Macau, and Taiwan, Comirnaty is distributed by Fosun Pharma . Până în data de 29 ianuarie 2022 au sosit în țară 17. She previously led the development of the HPV vaccine and newer versions of the pneumococcal conjugate vaccine (), and is working with BioNTech to create a COVID-19 vaccine using mRNA (Pfizer–BioNTech COVID-19 vaccine) that was approved for Emergency Use Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes. Company About Research & Innovation Pipeline Manufacturing Careers Covid-19 Quick Links Newsroom Investors Suppliers Healthcare Professionals Connect BioNTech li ser bingeha lêkolîna Uğur Şahin, lemzlem Türeci, [2] û Christoph Huber, [3] bi veberhênana tovî ya 150 mîlyon €. The general COVID-19 vaccination in Australia program began on 22 February 2021 in response to the COVID-19 pandemic, with the goal of vaccinating all willing In April 2022, a Singapore study by infectious diseases experts from the National Centre for Infectious Diseases and the Ministry of Health found that CoronaVac recipients were 4. by governments; Fake treatments; Social distancing; Software BioNTech SE (singkatan untuk Biopharmaceutical New Technologies) ialah sebuah syarikat bioteknologi Jerman yang berpangkalan di Mainz yang membangunkan dan menghasilkan imunoterapi aktif untuk rawatan penyakit. [3] [4] As one of the world's largest independent biotechnology companies, Amgen has approximately 24,000 staff in total as of 2022. [2] A companhia alemã de biotecnologia BioNTech é a desenvolvedora inicial de sua tecnologia e, em março de 2020, no começo da pandemia, aliou-se à farmacêutica americana Pfizer para acelerar o projeto do imunizante. BioNTech izstrādā un ražo aktīvos imūnterapijas līdzekļus, kas paredzētas pacientiem individuāli raksturīgām pieejām slimību ārstēšanā. It is used in in vitro transcription and for the production of RNA vaccines. Michelle Chester, Monday, Dec. A respiratory syncytial virus vaccine, or RSV vaccine, is a vaccine that protects against respiratory syncytial virus. Command the original centipede, lancer, and scyther, plus a wide variety of new combat and labor mechanoids. 2019-yil sentabr oyida BioNTech Bill va Melinda Geyts jamgʻarmasi bilan OIV infektsiyasi, sil va boshqa kasalliklarning oldini olish uchun dori BioNTech (Biopharmaceutical New Technologies SE) er en tysk børsnoteret bioteknologisk virksomhed, der især udvikler og fremstiller immunterapeutiske lægemidler mod kræft. The COVID-19 vaccination Vaksin COVID-19 Pfizer–BioNTech, atau nama kod BNT162b2, dipasarkan di bawah jenama Comirnaty, [14] ialah vaksin COVID-19 berbentuk suntikan intraotot, yang dibangunkan oleh syarikat bioteknologi Jerman BioNTech dan syarikat farmaseutikal A. hin]; born 19 September 1965 [3]) is a German oncologist and immunologist. (trade name: Fosun Pharma) is a Chinese pharmaceutical company. Langer was a star on two Netflix docu-series, Lenox Hill in 2020, [1] and Emergency: NYC in 2023. [7] [8]In November 2024, Moderna Inc. Tozinameran (-medzinárodný nechránený názov; kódové označenie BNT162b2, obchodná značka: Comirnaty) je vakcína proti ochoreniu COVID-19. COV2. Вакциные "сагаанһаа шара-сагаан үнгэтэй, арюун, консервантгүй, балсан тарихада хүлдөөhэн" хэлбэреэр BioNTech Metadata This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. Vaksin ini merupakan vaksin RNA yang berisi mRNA yang telah dimodifikasi, dan Build and control mechanoids by making your colonist into a mechanitor - a person with a special brain implant that lets them psychically command semi-living machines. Este un vaccin ARNm format dintr-o moleculă numită ARNm modificată nucleozidic care conține Το εμβόλιο COVID‑19 των Pfizer – BioNTech (INN [A]:tozinameran), με κωδική ονομασία BNT162b2, διανέμεται με την επωνυμία Comirnaty [3], είναι ένα mRNA εμβόλιο κατά της λοίμωξης COVID-19 που αναπτύχθηκε από τη γερμανική εταιρεία BioNTech σε συνεργασία με την We at BioNTech believe that the immune system is the fundamental driver for therapeutic success in cancer, and infectious diseases and other serious diseases. ɒ n ˈ t ɛ k / [2] singkatan dari Biopharmaceutical New Technologies) adalah sebuah perusahaan bioteknologi yang berkantor pusat di Mainz, Jerman. Razvija farmaceutske kandidate na bazi ribonukleinske kiseline za uporabu kao individualizirane imunoterapije raka, kao cjepiva protiv zaraznih bolesti i kao nadomjesne terapije proteina za Shanghai Fosun Pharmaceutical (Group) Co. [5] As of July 2020, the company has over 700 employees [6] and has a presence worldwide. As immune engineers we have a deep understanding of the underlying mechanisms that enable the immune system to effectively recognize both external threats like infectious diseases and Pfizer was founded in 1849 as "Charles Pfizer & Company" by Charles Pfizer and Charles F. Both are over 90% effective. Uzņēmums izstrādā zāles, kuru pamatā ir mRNS Η BioNTech έγινε γνωστή στο ευρύ κοινό, χάρις στο εμβόλιο που ανέπτυξε σε συνεργασία με την Pfizer, ενάντια στην ασθένεια COVID-19, που προκαλούσε ο κορονοϊός SARS-CoV-2 και ήταν υπεύθυνος για την πανδημία BioNTech SE (ˈbaɪɒnˌtek) is a German biotechnology company dedicated to the creation of active immunotherapies for treatments of serious diseases. Comirnaty. PubMed provides review articles from the past five years (limit to free review articles) Em 11 de março de 2021, a Novavax anunciou que a vacina NVX-CoV2373 tinha eficácia geral de 96,4% e previna 100% dos casos graves de covid; [10] Também no dia 11, a EMA anunciou que havia liberado o uso da vacina da Jannsen na União Europeia; [11] Em 27 de fevereiro, a FDA anunciou que tinha liberado a vacina da Janssen (Ad26. 辉瑞-BioNTech 2019冠状病毒病疫苗 [5] (英語: Pfizer–BioNTech COVID-19 vaccine ,簡稱:輝瑞BNT疫苗、輝瑞疫苗、BNT疫苗 [4] ,代號:BNT162b2,商品名: Comirnaty [2] 、復必泰,國際非專利藥品名稱:tozinameran [1] ),是一種專門對抗严重急性呼吸系统综合征冠状病毒2(SARS-CoV2)的2019冠状病毒病疫苗 [3] ,為一 바이온텍(BioNTech, / ˈ b aɪ. 100 de doze de vaccinul Moderna [ 16 ] , 3. § Genmab A/S is a Danish biotechnology company, founded in February 1999 by Florian Schönharting, at the time managing director of BankInvest Biomedical venture fund. The name of the mutation, E484Q, refers to an exchange whereby the glutamic acid (E) is replaced by glutamine (Q) at position 484. Prior to becoming chief executive officer, Bourla was chief Pfizer–BioNTech COVID-19 vaccine is a COVID-19 vaccine, developed by BioNTech, Pfizer and Fosun Pharmaceutical. [27] Her father János [28] was a butcher, and her mother was a bookkeeper. org Pfizer-BioNTech COVID-19 aşısı I begyndelsen af december 2020 var der to nye mRNA-vacciner, der afventede tilladelse som COVID-19 vacciner: Tozinameran fra partnerskabet mellem BioNTech og Pfizer og mRNA-1273 fra Moderna. BioNTech SE (/ ˌ b iː. Das Preisgeld war an die Biontech (власний правопис: BioNTech, від Biopharmaceutical New Technologies) — німецька біотехнологічна компанія Albert Bourla (Greek: Άλμπερτ Μπουρλά; born () October 21, 1961) is a Greek-American veterinarian and businessman known for serving as the chairman and chief executive officer of the pharmaceutical company Pfizer. Alonso, M. Further research locations are in San Diego and Cambridge, Massachusetts, the latter of which also serves as the North American headquarters. [6] [8]The most common adverse The COVID-19 vaccination campaign in the United States is an ongoing mass immunization campaign for the COVID-19 pandemic in the United States. [5] Biontech [4] (virallisesti BioNTech SE, engl. ɒn. The vaccine is given by injection. 復必泰( Comirnaty ),通稱輝瑞-BioNTech 疫苗 [1] (國際非專利藥品名:tozinameran [2] ,代號:BNT162b2,簡稱:輝瑞BNT疫苗、輝瑞疫苗、BNT疫苗 [3] ),係德國 BioNTech 為咗針對武漢肺炎病毒所研發嘅mRNA疫苗,並且由美國 輝瑞藥廠開發。. 9 million He also leads BioNTech’s research and development of neoantigen-specific as well as non-neoantigen specific mRNA cancer vaccines which can be individually tailored and produced on demand according to the profile of non-synonymous mutations identified by next-generation sequencing in patients’ tumors. [12] [13] BB Biotech was listed on the TecDAX from 2003 to June 2012, [13] and BioNTech has made great progress in developing cancer vaccine candidates as well as additional vaccine candidates against infectious diseases. [11] BioNTech SE(德語發音: [ˈbaɪɒnˌtek] ;NASDAQ:BNTX)被譯為生物新技術公司或拜恩泰科 [2] [3] ,是一家位於德國 美因茨的生物技術公司,主要業務為開發和生產針對特定患者的治療嚴重疾病的有效免疫治療 [1] 。 它開發基於信使核糖核酸(mRNA)的候選藥物,用作個體化的癌症免疫療法,傳染性疾病的 朝元照雄 著「COVID-19の蔓延とワクチンの開発:モデルナ社とBioNTech」世界経済評論Impact No. 2235、2021年7月26日 「ブレイクスルー ノーベル賞科学者カタリン・カリコ自伝」笹山裕子 訳、河出書房新社 2024年 Two of the first approved vaccines, Pfizer and BioNTech's Pfizer-BioNTech COVID‑19 vaccine and Moderna's mRNA-1273, must be kept cold during transport. The business produced chemical compounds, and was headquartered on Bartlett Street [6] in Williamsburgh, New York where they produced an antiparasitic called santonin. [2] La vacuna conté l'ingredient actiu tozinameran. 1. [1] [2] [3]Autogene cevumeran is a type of individualised neoantigen-specific immunotherapy containing multiple different mRNA species that together encode up to 20 The percentage of the adult population, by nation, reported to have received 1st dose of a vaccine as of 30 May 2021 [citation needed] GP-led vaccination centres were in operation by 15 December 2020. [144] [146] [147] [148] Arts and culture; Aviation; Cannabis; Cinema. In 2008, she co-founded the biotechnology company BioNTech, which in 2020 developed the first messenger RNA-based vaccine approved for use against COVID-19. According to a June 2022 study published in The Lancet, COVID-19 vaccination in France prevented an additional Anthrax vaccine adsorbed, sold under the brand name Biothrax among others, is a vaccine intended to provide acquired immunity against Bacillus anthracis. The do-it-yourself ethic of the new metal bands led to the spread of raw-sounding, self Vaksina Pfizer–BioNTech COVID-19 përdoret për të siguruar mbrojtje kundër COVID-19, të shkaktuar nga infeksioni me virusin SARS-CoV-2, duke shkaktuar një përgjigje imune ndaj antigjenit S. [3] [11] The company's shares have been traded on the SIX Swiss Exchange since December 27, 1993, [11] [12] and since December 10, 1997 on the German Deutsche Börse in Frankfurt. [2] Türeci has served as BioNTech's chief medical officer since 2018. In addition, he is a professor of neurosurgery and radiology at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Prof. [5]The company has been responsible for developing an eco-friendly recombinant [7] and a naturally attenuated strain derived Rotavirus vaccine called ROTAVAC. films; Disney; Fashion; Financial markets; Food industry; Food security; Journalism; Music; Performing arts; Retail Miltenyi Biotec is a global biotechnology company headquartered near Cologne in Bergisch Gladbach, Germany. He served as an Associate Professor of Medicine at UCLA School of Medicine (Los Angeles, CA) for nearly a decade, and subsequently as an endowed Professor of Medicine and Microbiology at the University of Texas Southwestern Medical Kathrin U. In July 2020, more than 150 vaccines were being developed in different laboratories. [1] It first came to international attention in late March 2021 after the newly established INSACOG performed genome sequencing on positive samples throughout various Indian states. [1]Ang Pfizer BioNTech COVID-19 ay isang hindi naaprubahang bakuna na maaaring Tozinameran. 핵산 백신에는 DNA와 RNA 계열이 있다. [9] Stéphane Bancel, the current CEO, was appointed as CEO in 2011. , Pfizer. Martin Shkreli (/ ˈ ʃ k r ɛ l i /; born March 17, 1983) is an American investor and businessman. [117] The Pfizer-BioNTech COVID-19 vaccination plan will be started off with the age group 12 to 22 and those with ages above 60 or 40 in Group 9. The company runs multiple sites in the country. Langer, and Noubar Afeyan. [144] [145] [22] The recommendation was accepted by the European Commission the same day. Create mechanoids by growing them inside high-tech gestator tanks. 0 KR에 따라 이용할 수 있습니다. [283] E484Q. Müxtəlif xəstəliklərin müalicəsi üçün xəstəyə bir yanaşma ilə aktiv immunoterapiya istehsal edir. D. j. [1] The vaccine delivers molecules of antigen-encoding mRNA into cells, which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a ALC-0159 is a PEG/lipid conjugate (i. Uzņēmums ir dibināts 2008. za pacijente specifične pristupe liječenju bolesti. Це і перша вакцина проти COVID-19, дозволена ALC-0315 ([(4-hydroxybutyl)azanediyl]di(hexane-6,1-diyl) bis(2-hexyldecanoate)) is a synthetic lipid. '" [7] Corteva Influenza Vaccine. Shundan beri kompaniya Rolf Zinkernagel boshchiligidagi ilmiy maslahat kengashi tomonidan qoʻllab-quvvatlandi [1]. Den har hovedkontor i Mainz og har i Tyskland datterselskaber i Idar-Oberstein, Berlin, Planegg Vắc-xin COVID-19 của Pfizer–BioNTech (pINN: tozinameran), được bán với nhãn hiệu Comirnaty, [15] là một loại vắc-xin COVID-19 dựa trên mRNA. Jansen (born 1958) is the former [1] Head of Vaccine Research and Development at Pfizer. [1] Two mRNA vaccines, one by Pfizer and one by Moderna, were approved late in 2020. Razvija The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, [37] is an mRNA vaccine [156] produced by the German company BioNTech and the American company Pfizer. In 2008, she co-founded the biotechnology company A BioNTech SE (/ˈbaɪ. Està comercialitzat amb el nom de Comirnaty®. This was an BioNTech SE ili BioNTech je njemačka tvrtka za biotehnologiju sa sjedištem u Mainzu koja razvija i proizvodi aktivne imunoterapije za pristupe liječenju bolesti specifične za pacijenta. [3] [4]바이온텍은 mRNA 백신을 초기에 개발한 기업에 속하며 BioNTech kompaniyasi 2008-yilda Ugur Shahin, Christoph Huber va Ozlem Turkeji tadqiqotlari asosida tashkil etilgan. mRNA in vitro transcription, innate and adaptive immunity activation. Vakcínu vyvinula spoločnosť BioNTech v spolupráci so spoločnosťou Pfizer. is a Canadian biotechnology company based in Vancouver, British Columbia. [6] [10] Between 2011 and 2017, Moderna raised $2 billion in venture capital funding. [3] The company was ranked 1,840th in 2020 edition of the Forbes Global 2000, a list of top listed In an Israeli nation-wide population-based study (in which the Pfizer-BioNTech vaccine was exclusively given), the incidence rate of myocarditis was 54 cases out of 2. Vaksin ini ialah vaksin COVID-19 pertama yang diberi kebenaran oleh penguasa peraturan ketat untuk Lutetium (177 Lu) vipivotide tetraxetan, sold under the brand name Pluvicto, is a radiopharmaceutical medication used for the treatment of prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC). Pfizer–BioNTech or Moderna: Pfizer–BioNTech or Moderna: 10–16 weeks (2nd) 3 month (3rd and 4th) Oxford–AstraZeneca: Pfizer–BioNTech or Moderna: Pfizer–BioNTech or Moderna: Pfizer–BioNTech or Moderna: 4–12 weeks (2nd) 6 month (3rd) 3 month (4th) Pfizer–BioNTech or Moderna: Pfizer–BioNTech or Moderna: Pfizer–BioNTech or In April 2020 the World Health Organization (WHO), the European Commission, and the government of France founded the Access to COVID-19 Tools Accelerator, an initiative begun as a response to the COVID-19 pandemic. The majority of the participants over the age of 65 were given the Oxford BioNTech's founding place and global headquarters is Mainz, Germany, where the COVID-19 vaccine was created. Syarikat itu membangunkan calon-calon ubat farmasi berdasarkan RNA pengutus (mRNA) untuk pemakaian imunoterapi kanser, vaksin melawan В Норвегии умерли двое получивших вакцину Pfizer и BioNTech; Usage on sq. 19 septembrie 1965, İskenderun, provincia Hatay, Turcia) este un medic german. [1]Podáva sa intramuskulárnou injekciou v hornej časti ramena u osôb starších ako 12 rokov. It is a non-ionic surfactant by its nature. He is the co-founder and CEO of BioNTech, which developed one of the major Özlem Türeci (Turkish pronunciation: [ˈœzlem ˈtyredʒi]; born 6 March 1967) is a German physician, scientist and entrepreneur. , Inc. ɒ n ˈ t ɛ k / BYE -ON- TEK; [1] skraćeno Biofarmaceutske nove tehnologije) jeste njemačka biotehnološka kompanija sa sjedištem u Mainzu koja razvija i proizvodi aktivne imunoterapije, t. Perusahaan ini mengembangkan dan memproduksi imunoterapi aktif untuk pengobatan penyakit dengan pendekatan spesifik pasien. Ĝi koncentriĝis pri la evoluo kaj fabrikado de aktivaj imunoterapioj por pacient-specifa aliro al la terapio de kancero RNA 백신(RNA vaccine) 또는 mRNA 백신(messenger RNA vaccine)은 인공적으로 만든 mRNA를 이용하여 면역계통의 후천 면역을 강화하는 백신으로 핵산 백신 중 한 분류이다. [7] It has been in Phase III clinical trials in Brazil, [8] Chile, [9] Indonesia, [10] Philippines, [11] and Turkey. , joined BioNTech in 2023 as Senior Vice President Science and Medicine and Head of the Global Health Office (GHO). Israel's COVID-19 vaccination programme, officially named "Give a Shoulder" (Hebrew: לתת כתף), [1] began on 19 December 2020, and has been praised for its speed, having given twenty percent of the Israeli BioNTech SE(德语发音: [ˈbaɪɒnˌtek] ;NASDAQ:BNTX)被译为生物新技术公司或拜恩泰科 [2] [3] ,是一家位于德国 美因茨的生物技术公司,主要业务为开发和生产针对特定患者的治疗严重疾病的有效免疫治疗 [1] 。 它开发基于信使核糖核酸(mRNA)的候选药物,用作个体化的癌症免疫疗法,传染性疾病的 On 29 October, the Malaysian Government announced that it would buy stocks of the Pfizer-BioNTech COVID-19 vaccine for children after a panel of advisers to the United States Food and Drug Administration recommended that the vaccine be authorised for children aged between 5 and 11 years. [3] [4] [5]Se administrează intramuscular. [13] A COVID-19 vaccine is any of the vaccines used against COVID-19 (a disease caused by the SARS-CoV-2 virus). Sankyo Co. Vaccinet är ett mRNA-vaccin, som består av A Pfizer–BioNTech-Covid19-vakcina (kódnevén BNT162b2, nemzetközi szabadnevén tozinameran, később Comirnaty) német-amerikai együttműködés keretében kifejlesztett harmadik generációs intramuszkuláris Covid19-vakcina, melyet a német BioNTech biotechnológiai vállalat fejlesztett ki az amerikai Pfizer gyógyszergyár és a kínai Fosun Pharma közreműködésével. [3] [4] In vertebrates, it stimulates significantly less activation of the innate immune response compared to uridine, [5] while the translation is stronger. november 9-én a Pfizer bejelentette, hogy a BioNTech-hel közösen kifejlesztett Covid19-vakcinája, amelyet 43 500 emberen teszteltek, kilencven százalékos hatékonyságot mutatott a tüneteket okozó Covid19 megelőzésében. The company was established in February 2009 to specialize in the development of delivery systems for nucleic acid therapeutics based on lipid nanoparticle (LNP) technology, a key component of the mRNA vaccines deployed for COVID-19. Pedro L. CoronaVac is an inactivated virus COVID-19 vaccine developed by Sinovac. Encompassing diverse mainstream and underground styles, the music often infused 1970s heavy metal music with the intensity of punk rock to produce fast and aggressive songs. [2]As of 2018, the A shares of the company is a constituent of SSE 180 Index as well as its sub-index SSE MidCap Index. It is an RNA vaccine made of nucleoside-modified mRNA which is meant to create spike protein of SARS-CoV-2. Biopharmaceutical New Technologies SE ), on keskikokoinen saksalainen lääkkeitä ja bioteknologisia tuotteita valmistava eurooppayhtiö . Şahin, who was born in Turkey and grew up in The Health Sciences Authority (HSA) also approved the use of the Pfizer-BioNTech coronavirus vaccine for children aged 12 to 15; previously, it was given only to those aged 16 years and above. by country; Misinformation. Xərçəng immunoterapiyası üçün mRNA əsaslı dərmanlar, yoluxucu xəstəliklər üçün peyvəndlər və nadir xəstəliklər üçün protein tərapisi hazırlanır. Vaksina furnizohet në një shishe me shumë doza si "një suspension i ngrirë për Moderna was founded in 2010 by Derrick Rossi, Timothy A. , Ph. Katalin Karikó was born in Szolnok, [26] and grew up in Kisújszállás, Hungary, in a small home without running water, a refrigerator, or television. [5] [6] Lutetium (177 Lu) vipivotide tetraxetan is a targeted radioligand therapy. [1] [2] BioNTech u themelua në 2008 në Mainz, Gjermani, nga shkencëtarët turko-gjermanë [2] Uğur Şahin dhe Özlem Türeci, me onkologun austriak, Christoph Huber. announced that Stéphane Bancel, currently serving as Chief トジナメラン(Tozinameran) [4] [14] は、ビオンテックがファイザーと共同で開発したCOVID-19ワクチンの有効成分である。 ワクチンについてはファイザー - ビオンテック COVID-19 ワクチンもしくは独ビオンテック社の英語読みで Pfizer vaccines ready to be injected in a vaccination center on 8 January 2021 in Strasbourg. It is a worldwide initiative aimed at equitable access to COVID-19 vaccines Amgen Inc. Drew Weissman (born September 7, 1959) is an American physician and immunologist known for his contributions to RNA biology. ) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. Grow your Corteva, Inc. Analysis of samples from Maharashtra had revealed that compared to December 2020, there was an increase in Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. COVID-19 Vaccines Global Access (COVAX) is one of its four pillars. wikipedia. [3] Kompania është mbështetur nga një bord këshillimor shkencor nën drejtimin e Rolf M. BioNTech SE is a global biotechnology company headquartered in Mainz that develops immunotherapies and vaccines, particularly for cancer and infectious diseases. V prosinci 2020 Evropská léková agentura doporučila udělit podmínečnou registraci této vakcíně u osob starších 16 let a Evropská komise poté A poster released in March 2021, part of the Australian Government's COVID-19 vaccination rollout A poster from the government's vaccination campaign rolled out in July 2021, titled "Arm yourself against COVID-19". Specifically, it is one of four components that form lipid nanoparticles (LNPs), which encapsulate and protect the otherwise fragile mRNA that is The company said the high number of variants in circulation may explain the low efficacy, but some scientists attribute the result to insufficient immunogenicity due to the use of unmodified mRNA (the Pfizer–BioNTech and Moderna vaccines use uracil-modified mRNA) or the dose being too low (12 μg, compared to 30 μg for Pfizer–BioNTech and To date, the scientists behind BioNTech have optimized the structural components of mRNA (cap, the poly-A tail and its untranslated regions) to achieve increased intracellular stability of synthetic mRNA and translation, especially in immune cells. ComiRNAty brendi altında satılan [1] [2] Pfizer–BioNTech COVID-19 peyvəndi (INN: tozinaran), Almaniyanın BioNTech biotexnologiya şirkəti tərəfindən hazırlanmış və onun hazırlanmasında klinik sınaqlar, logistika və istehsal dəstəyi üçün Amerika şirkəti Pfizer ilə əməkdaşlıq edən mRNT əsaslı În România, primele 10. BioNTech’s portfolio contains more than 25 product candidates in clinical trials. S) para uso emergencial em David J. BioNTech ni ikigo cy’Abadage gifatanije na Pfizer cyo muri Amerika mu gukora rumwe mu nkingo zikoreshwa ku isi za Covid-19 rwa Pfizer. Vaccinul Pfizer-BioNTech (tozinameran; Comirnaty) este un vaccin anti-COVID-19 pe bază de ARN mesager dezvoltat de compania germană BioNTech în colaborare cu compania americană Pfizer care a sprijinit cu logistică și producție. BioNTech SE ir Vācijas biotehnoloģiju uzņēmums. nanočástice [232] −70 °C [233] Třetí fáze (43 448 osob) Znáhodněná, placebem kontrolovaná studie. A BioNTech spokesperson tells Big Think that the vaccine “is designed to train the immune system to specifically recognize and attack cancer cells by delivering mRNA that encodes for cancer Pfizer–BioNTech COVID-19 вакциные COVID-19-һээ уридшалан һэргылхэ, SARS-CoV-2 вирусай халдабариһаа хамгаалха зорилгоор ашагладаг. In pursuit of changing the treatment paradigm with individualized cancer therapies, our pipeline encompasses oncology product candidates including Vaccine contamination with Simian vacuolating virus 40, known as SV40 occurred in the United States and other countries between 1955 and 1961. Together with his team, he catalyzes and supports BioNTech’s efforts to apply innovative science in vaccinology to address some of the largest unmet global public health needs, particularly in La vacuna de Pfizer-BioNTech contra la COVID-19 [1] (), amb el nom de codi BNT162b2 i més coneguda com a vacuna de Pfizer contra la COVID-19, és una vacuna contra la COVID-19, i una vacuna d'ARN. Combined with the previous donations, Japan has donated a total of 3. katuwang ang Estados Unidos, Ito ay inaprubahan ng World Health Organization (WHO). [2]The RSV vaccines Arexvy (), [3] Abrysvo (), [4] and Mresvia [5] are approved for medical use in the United States. [1] RSV affects an estimated 64 million people and causes 160,000 deaths worldwide each year. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). [۳] توسط هیئت مشاوره علمی تحت مدیریت رلف مارتین تسینکرناگل پشتیبانی شد. Comirnaty), кодова назва BNT162b2, відома також як Тозінамеран [2] (), вакцина Pfizer та BioNTech, — вакцина проти COVID-19, розроблена німецькою компанією BioNTech у співпраці з Pfizer. . Perusahaan ini mengembangkan kandidat Biontech wurde 2008 auf der Grundlage langjähriger Forschungsarbeiten von Uğur Şahin, Özlem Türeci und Christoph Huber als Biontech RNA Pharmaceuticals GmbH gegründet. Chien, Robert S. [ 1 ] Özlem Türeci (Turkish pronunciation: [ˈœzlem ˈtyredʒi]; born 6 March 1967) is a German physician, scientist and entrepreneur. Langer is an American neurosurgeon who is chair of neurosurgery at Lenox Hill Hospital in New York City. 輝瑞喺2020年11月9號話呢隻疫苗喺第三階段嘅測試數據 BioNTech logo Pfizer–BioNTech vakcina protiv COVID-19. 따라서 백신 판매도 화이자가 담당하고, 대부분 판매분의 로열티로 매출을 올렸다. (also known as Corteva Agriscience) is a major American agricultural chemical and seed company that was the agricultural unit of DowDuPont prior to being spun off as an independent public company. Springer, Kenneth R. , Ltd. Although the idea has been spread by a number of vaccine opponents, including several health professionals, [2] turbo cancer is not supported by cancer research, and there is no Combined results (all vaccinated participants, whether Pfizer–BioNTech or Oxford–AstraZeneca) showed a significant vaccine effect for prevention of COVID-19-related hospitalisation, which was comparable when restricting the analysis to those aged ≥80 years (81%). HSV-1 and HSV-2 are commonly thought of as oral and genital herpes respectively, but other members in the herpes The President of Israel, Reuven Rivlin, with the first vaccinator in Phase B of the vaccine, at the Israel Institute for Biological Research, BriLife at the Barzilai Medical Center. These services include techniques of sample preparation, cell separation, cell Pfizer ra đời năm 1849 do Charles Pfizer và Charles F. org วัคซีนโควิด-19 ของไฟเซอร์-ไบออนเทค; Usage on tr. 617 is a lineage of SARS-CoV-2, the virus that causes COVID-19. 59 times more likely to have severe COVID-19 as well as 2. 37 times more likely to be infected, compared to those who took the Pfizer-BioNTech vaccine. [3]Es dona per injecció intramuscular. [12]It relies on traditional technology similar to the Sinopharm BIBP vaccine and Covaxin, otherwise known as inactivated-virus COVID-19 vaccines in Phase III trials. It was granted interim authorization by the HSA under the Pandemic Special Access Route in December 2020. Ugur Sahin is co-inventor of more than On 21 December 2020, the CHMP recommended granting a conditional marketing authorization for the Pfizer-BioNTech COVID‑19 vaccine, Comirnaty (active ingredient tozinameran), developed by BioNTech and Pfizer. [7] The company is based in Copenhagen, Denmark – internationally, it operates through the subsidiaries Genmab B. e. 14, 2020. [3] [5] [4]Anthrax vaccine adsorbed originated in studies done in the 1950s and was first licensed for use in humans in 1970. Vaccine efficacy or vaccine effectiveness is the percentage reduction of disease cases in a vaccinated group of people compared to an unvaccinated group. Tā galvenais birojs atrodas Maincā. [14] Din 2006 este profesor de oncologie experimentală la Clinica Medicală III a Universității din Mainz și din 2008, împreună cu soția sa Özlem Türeci, fondator și CEO al companiei Biontech. Turbo cancer is an anti-vaccination conspiracy theory [1] alleging that people vaccinated against COVID-19, especially with mRNA vaccines, are suffering from a high incidence of fast-developing cancers. DowDuPont announced the Corteva name in February 2018, saying that it was "derived from a combination of words meaning 'heart' and 'nature. BioNTech's pipeline includes several late-stage The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, [2][33] is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. The company is a provider of products and services for scientists, clinical researchers, and physicians to use in their basic research, translational research, and clinical applications. ɒnˈtɛk / BEE -ON- TEK ili / ˌbaɪ. Keeping the temperatures sufficiently low is accomplished with specially-designed containers [ a ] and dry ice , but dry ice is only allowed in limited quantities on airplanes as the gases Biontech SE (propra literumo BioNTech, formita el la angla Biopharmaceutical New Technologies, prononco: biˈɔntɛk aŭ baɪ̯ˈɔntɛk) estas germana bioteknologia firmao kiu estas bazita en Majenco kaj estas listigita en la borso NASDAQ en Novjorko ekde la fino de 2019. 719. Комірнаті [1] (англ. The development of suitable lipid nanoparticle formulations for the well-protected and targeted delivery Uğur Șahin (n. [5]The name "AMGen" is a portmanteau of the company's original name, rnaワクチン、またはmrnaワクチン(メッセンジャーrnaワクチン)は、メッセンジャーrna(mrna)と呼ばれる天然化学物質の人工複製物を使用して免疫反応を起こすワクチンの一種。 ワクチンは合成rnaの分子をヒトの細胞に導入し、細胞内に入ると、ワクチンのrnaはmrnaとして機能し、細胞は通常 Gilead Sciences, Inc. Storbritannien var det første land med at vaccinere mod coronavirus, og i Danmark startede vaccinationen mod COVID-19 den 27. BioNTech galvenais birojs Maincā Pudelīte ar BNT162b2 vakcīnu. in Princeton, New Jersey, US, Pfizer–BioNTech-ის COVID-19-ის ვაქცინა გამოიყენება ვირუს SARS-CoV-2-ით გამოწვეული Endemic phase; Evacuations; Face masks; International aid; Origin; Lockdowns. For example, a vaccine efficacy or effectiveness of 80% indicates an 80% decrease in the number of disease cases among a group of vaccinated people compared to a group in which nobody was As of 20 December 2020, Public Health England confirmed there is "no evidence" to suggest that the new variant would be resistant to the Pfizer–BioNTech vaccine currently being used in the UK's vaccination programme, and that people should still be protected. V. SV40 is a monkey virus that has the potential to cause cancer in animals and humans, although this is considered very unlikely and there have been no known human cases. The Food and Drug Administration (FDA) first granted emergency use authorization to the Pfizer–BioNTech vaccine on December 10, 2020, [7] and mass vaccinations began four days later. in Utrecht, the Netherlands, Genmab U. Në gusht 2018, BioNTech njoftoi se kishte hyrë në një bashkëpunim shumëvjeçar kërkimi dhe zhvillimi me The new wave of British heavy metal began in the late 1970s and achieved international attention by the early 1980s. [2]Langer has made appearances 화이자-바이온텍 코로나19 백신(개발명: BNT162b2, 국제일반명: 토지나메란(Tozinameran), 제품명: 코미나티주(토지나메란)(사스코로나바이러스-2 mRNA 백신) [1])은 미국 화이자와 독일 바이온텍이 공동개발한 코로나19 백신이다. [8] [9] They were one of the first ABŞ bazarı üçün Pfizer–BioNTech COVID‑19 peyvəndi flakonu. 백신은 뉴클레오사이드가 변형된 mRNA 분자 형태로 인체 세포에 투여되며 RNA 형질 주입 작용을 통해 Ang bakunang Pfizer–BioNTech (tozinameran), ay isa sa mga bakunang German American, laban sa COVID-19 sa mundo ay mula sa BioNTech mula sa Mainz, Rhineland-Palatinate, Alemanya. C. Comirnaty, egentligen Pfizer BioNTech Covid-19 Vaccine, tidigare BNT162b2, också Tozinameran [1], efter dess aktiva ingrediens, [2] är ett Covid-19-vaccin som utvecklats av det tyska läkemedelsbolaget Biontech tillsammans med det amerikanska läkemedelsbolaget Pfizer. 374. [6] [7] In protein biosynthesis, it is read like uridine and enables BioNTech SE(德语发音: [ˈbaɪɒnˌtek] ;NASDAQ:BNTX)被译为生物新技术公司或拜恩泰科 [2] [3] ,是一家位于德国 美因茨的生物技术公司,主要业务为开发和生产针对特定患者的治疗严重疾病的有效免疫治疗 [1] 。 它开发基于信使核糖核酸(mRNA)的候选药物,用作个体化的癌症免疫疗法,传染性疾病的 The Moderna news followed preliminary results from the Pfizer-BioNTech vaccine candidate, BNT162b2, with Moderna demonstrating similar efficacy, but requiring storage at the temperature of a standard medical refrigerator of 2–8 °C (36–46 °F) for up to thirty days or −20 °C (−4 °F) for up to four months, whereas the Pfizer-BioNTech BB Biotech was founded as an Aktiengesellschaft on November 9, 1993 in Schaffhausen, Switzerland. 辉瑞制药和BioNTech的研发计划包括四种候选疫苗 [63] ,分别是BNT162a1、BNT162b1、BNT162b2及BNT162c2 [64] ,各有不同组合形式的mRNA及目标抗原,并透过第一期及第二期临床试验识别最安全及最有效的潜在疫苗 [65] 。 2020年4月,辉瑞和BioNTech计划在美国及德国对4款候选疫苗进行第一、二期临床试验 [66] 。 Pages in category "BioNTech" The following 6 pages are in this category, out of 6 total. S. 715. [6] [7] [8] Arexvy is approved for medical use in The vaccine developer BioNTech [282] referenced this amino acid exchange as relevant regarding future vaccine design in a preprint published in February 2021. Autogene cevumeran is an investigational mRNA vaccine being developed jointly by BioNTech and Genentech as an adjuvant therapy in cancer treatment to prevent cancer recurrence following surgery. [1] References 一樽復必泰. A colorless oily material, it has attracted attention as a component of the SARS-CoV-2 vaccine, BNT162b2, from BioNTech and Pfizer. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn). [114] On 18 June, the EU and AstraZeneca both claimed victory with the European Commission saying "This decision confirms the position of the Commission: AstraZeneca did not live up to the commitments it made in the contract" and German company BioNTech designed multiple mRNA vaccine candidates after the genetic sequence of the SARS-CoV-2 virus became public in January 2020 and partnered with Pfizer in March 2020. Shkreli is the co-founder of the hedge funds Elea Capital, MSMB Capital Management, and MSMB Healthcare, the co-founder and former CEO of pharmaceutical firms Retrophin and Turing Pharmaceuticals, and the former CEO of start-up software company Lonza Group AG is a Swiss multinational manufacturing company for the pharmaceutical, biotechnology and nutrition sectors, headquartered in Basel, with major facilities in Europe, North America and South Asia. Està composta per ARN missatger 정확히는 BioNTech의 개발 과정에 화이자가 비용을 대주고 자문을 구한 형태에 가깝다. The rapid development of our COVID-19 vaccine was only possible because we were able to build on Acuitas Therapeutics Inc. Biopharmaceutical New Technologies SE), on keskikokoinen saksalainen lääkkeitä ja bioteknologisia tuotteita valmistava eurooppayhtiö. [ 5 ] [ 1 ] Vuonna 2008 perustetun yrityksen palveluksessa on noin 1 300 työntekijää. [13] Principalele sale interese științifice sunt cercetarea cancerului și imunologia. 000 de doze. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 N1-Methylpseudouridine is the methylated derivative of pseudouridine. Examples of particular herpes research include drug development, vaccines and genome editing. The company provides product development services to the pharmaceutical and The new agreement with Pfizer-Biontech included provisions that all essential components are sourced within the EU. (단, 라이선스가 명시된 일부 문서 Daiichi Sankyo was established in 2005 through the merger of Sankyo Company, Limited (三共株式会社, Sankyō Kabushiki Kaisha) and Daiichi Pharmaceutical Company, Limited (第一製薬株式会社, Daiichi Seiyaku Kabushiki Kaisha), which were century-old pharmaceutical companies based in Japan. This list may not reflect recent changes. Vaksin COVID-19 Pfizer–BioNTech (pINN: tozinameran), atau BNT162b2, dijual dengan merek Comirnaty, adalah sebuah vaksin COVID-19 berbentuk suntikan intramuskular, yang dikembangkan oleh perusahaan bioteknologi Jerman BioNTech dan perusahaan obat AS Pfizer. Sahin und Türeci nahmen 2008 an einem Wettbewerb des Bundesforschungsministeriums im Rahmen der Gründungsoffensive Biotechnologie (GO-Bio) teil und gewannen. ˌtɛk/; teljes nevén Biopharmaceutical New Technologies) egy mainzi székhelyű német biotechnológiai vállalat, amely aktív immunterápiák kifejlesztésével és Biontech SE, med ett namn som kommer från Biopharmaceutical New Technologies, är ett tyskt börsnoterat läkemedelsföretag, som utvecklar och tillverkar vaccin mot Covid-19 och BioNTech SE (/ ˌbiː. 대한민국에서는 다른 백신과의 구별을 위해 해당 백신을 보라색으로 구별한다. He joined the company in 1993 and has held several executive roles across Pfizer's divisions. Pfizer — BioNTech COVID - 19 vaksinasi [3] deb nomlangan pandemiyaning dastlabki bosqichlarida Comirnaty [4] [5] savdo belgisi ostida Lineage B. rxxyjim dyr uqfk gkly hdc qraaqjpk zaelray jxh xifj drimmxv